These are in order from least shocking to most shocking according to the current lines at the Caesars Sportsbook.
| Georgia Southern (+3.0) at South Alabama- (Th) 7:30 |
| Jacksonville (+3.5) vs. Miami- (Sun) 9:30 AM |
| Indiana (+4.5) vs. Michigan State- 12:00 |
| Seattle (+4.5) at Pittsburgh- (Sun) 8:20 |
| Central Michigan (+4.5) vs. Toledo- 3:30 |
| Virginia Tech (+5.0) vs. Pittsburgh- 3:30 |
| Kansas State (+6.5) vs. Iowa State- 7:30 |
| Arizona (+7.5) at Colorado- 3:30 |
| Missouri (+8.5) vs. Texas A & M- 12:00 |
| LSU (+10.0) vs. Florida- 12:00 |
| Kansas (+16.5) vs. Texas Tech- 4:00 |
Last week’s Upset Pick of the Week: UTSA (+3.5) over Western Kentucky
