These are in order from least shocking to most shocking according to the current lines at the ESPN Bet Sportsbook.
| Arizona State (+3.0) at Texas Tech- 3:30 |
| Western Kentucky (+3.0) vs. Toledo- 7:00 |
| Atlanta (+5.0) vs. Kansas City- (Sun) 8:20 |
| Michigan (+5.5) vs. Southern Cal- 3:30 |
| Southern Miss (+6.0) at Jacksonville State- 3:00 |
| Ball State (+6.5) at Central Michigan- 1:00 |
| East Carolina (+7.0) at Liberty- 6:00 |
| Michigan State (+7.0) at Boston College- 8:00 |
| LA Rams (+7.5) vs. San Francisco- (Sun) 4:25 |
| Navy (+9.5) vs. Memphis- 3:30 |
Last week’s Upset Pick of the Week: Toledo (+9.5) over Mississippi State
