These are in order from least shocking to most shocking according to the current lines at the ESPN Bet Sportsbook.
| Florida Atlantic (+3.0) at UTSA- 3:30 |
| West Virginia (+3.0) vs. Kansas State- 7:30 |
| Tampa Bay (+3.5) vs. Baltimore- (Mon) 8:15 |
| Western Kentucky (+3.5) at Sam Houston- (Wed) 7:00 |
| Louisville (+4.0) vs. Miami-FL- 12:00 |
| Florida State (+4.0) at Duke- (Fri) 7:00 |
| Northwestern (+6.5) vs. Wisconsin- 12:00 |
| Nebraska (+7.0) at Indiana- 12:00 |
| Boston College (+7.0) at Virginia Tech- (Th) 7:30 |
| Oregon State (+7.5) vs. UNLV- 10:00 |
| Georgia Southern (+10.0) vs. James Madison- 4:00 |
Last week’s Upset Pick of the Week: Vanderbilt (+14.0) over Kentucky
