These are in order from least shocking to most shocking according to the current lines at the ESPN Bet Sportsbook.
| Iowa (+3.5) at Iowa State- 12:00 |
| Ohio (+3.5) vs. West Virginia- 4:00 |
| Western Kentucky (+6.5) at Toledo- 7:00 |
| UConn (+6.5) at Syracuse- 12:00 |
| Mississippi State (+6.5) vs. Arizona State- 7:30 |
| Western Michigan (+9.5) vs. North Texas- 3:30 |
| South Alabama (+10.5) vs. Tulane- 7:00 |
| Kentucky (+10.5) vs. Ole Miss- 3:30 |
| Rice (+13.5) vs. Houston- 7:00 |
| Northern Illinois (+17.5) at Maryland- (Fri) 7:30 |
Last week’s Upset Pick of the Week: LSU (+4.5) over Clemson
