Now that I have thoroughly analyzed the upcoming college football season, it is time for me to publish my seventh annual NFL preseason football guide. Much like my college preview, I have gone through and analyzed every NFL team’s regular season and postseason, as well as selected my disappointment and surprise teams, upsets to watch out for, and over/under win totals to bet.
As you can see from my main team preview articles, I predict the outcome of every regular season game that will be played this season, and these are the outcomes which based on the current Vegas lines are considered the biggest upsets. This year’s upset picks are listed below in chronological order, and the (H), (A), and (N) monikers written on each line represents whether or not the the team pulling off the upset is playing the game at home, away from home, or at a neutral site. Feel free to comment or debate on this post as well as any others included in this preview guide.
| Preseason Upset Picks of the Year | |
| 1 | New Orleans (A) over Detroit- Sun. Sept. 13 (1:00) |
| 2 | Indianapolis (H) over Baltimore- Sun Sept. 13 (1:00) |
| 3 | Tennessee (H) over Philadelphia- Sun. Sept. 20 (1:00) |
| 4 | Denver (H) over LA Rams- (Sun) Sept. 27 (8:20) |
| 5 | Cleveland (H) over Pittsburgh- Thurs. Oct. 1 (8:15) |
| 6 | Miami (A) over Minnesota- Sun. Oct. 4 (4:05) |
| 7 | Las Vegas (H) over Kansas City- Sun. Oct. 4 (4:25) |
| 8 | LA Chargers (A) over Seattle- Sun. Oct. 4 (4:25) |
| 9 | Arizona (H) over Detroit- Sun. Oct. 11 (4:25) |
| 10 | Buffalo (A) over LA Rams- Mon. Oct. 12 (8:15) |
| 11 | Las Vegas (H) over Buffalo- Sun. Oct. 18 (4:25) |
| 12 | Miami (H) over New England- Sun. Nov. 1 (4:25) |
| 13 | Atlanta (N) over Cincinnati- Sun. Nov. 8 (9:30 AM) |
| 14 | Cleveland (H) over Houston- Sun. Nov. 15 (1:00) |
| 15 | Las Vegas (H) over Seattle- Sun. Nov. 15 (4:05) |
| 16 | Cincinnati (A) over Pittsburgh- Sun. Nov. 15 (8:20) |
| 17 | Carolina (H) over Baltimore- Sun. Nov. 22 (1:00) |
| 18 | Minnesota (N) over San Francisco- Sun. Nov. 22 (8:20) |
| 19 | Cleveland (H) over Cincinnati- Sun. Dec. 6 (1:00) |
| 20 | NY Giants (H) over San Francisco- Sun. Dec. 6 (1:00) |
| 21 | NY Jets (H) over Denver- Sun. Dec. 13 (1:00) |
| 22 | NY Jets (H) over New England- Sun. Dec. 27 (1:00) |
| 23 | Miami (H) over Buffalo- Sun. Jan. 3 (1:00) |
| 24 | Arizona (H) over San Francisco- Sun. Jan. 10 (TBD) |
| 25 | NY Giants (H) over Philadelphia- Sun. Jan. 10 (TBD) |
